I think instead of taking billions of stars we should look at the "alien life" from the aspect of chemistry and biology.

What is the basic chemistry and biology of life? Chemicals, heat, water, single celled organisms, multi cellular organisms, bacteria, viruses, genetic materials, gene transfers etc. All of that in the context of universe, stars and planets.

I would like to see a research from that point of view. If anybody knows of such research papers I would like to read them.