At the scale of electron-sized particles, local reality no longer definitely exists. In fact, we have a chunk of math (Bell's inequalities) which suggests that local reality
cannot exist; either some parts of reality are non-local, or some parts of local interactions are non-real.
I say this because it undermines your hope that epistemology and metaphysics is merely a matter of explaining where electrons "come from"; the question is so wrong that it must be entirely rethought. An electron isn't a dot in space, but a behavior smeared throughout a region.
I thought that the reason that folks didn't like science is because they were preoccupied with Jehovah/etc. but perhaps I'm wrong.