I've used this to provide simple UIs to scripts for consulting projects where something more complex wasn't justified.

It mostly works great. If you have a complicated UI with multi-selects, validations and default selections, it probably isn't for you. But if you really just need a desktop UI for a script, it does what it says. You can make a UI in a few minutes.

There's also Wooey - a web-based take on the same idea if you need a Django web app to queue up and run your scripts. That implementation is a little more janky, but it also mostly works.