Anthony Fauci’s emails: ‘All is well despite some crazy people in this world’
washingtonpost.com
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We should continue to search for the reservoir animal and continue to pressure China to provide blood tests from researchers at the Wuhan lab. Without either exculpatory evidence for the Wuhan lab or clear evidence that it was a reservoir animal, the Wuhan lab leak theory should not be dismissed
Fauci was still saying [1] a reservoir animal was the most likely cause of the jump to humans a few days ago, despite having contrary evidence before almost anyone else.
I don't know why he isn't qualifying that more, but it's hard to see how it's not politics.
[0]https://twitter.com/JamesCTobias/status/1399811395043004418/...
[1]: https://twitter.com/JamesCTobias/status/1399882478488334337
The linked Nature paper in the third tweet [0] may demonstrate why a reservoir animal is more likely than the virus being artificially engineered, but damned if I can understand the reasoning in it. Maybe someone with a biology background or just plain smarter than me can explain it better.
In any case, my original point still stands, without exculpatory evidence for the Wuhan lab or the discovery of a reservoir animal, the lab leak theory should not be dismissed and any attempt to do so is just politics.
this means passing the pathogen from one individual to others then selecting based on desired character to inocculate the next cohort of hosts; this will amplify the frequency of the desired character.
this process will also occur naturally, accompanied by natural selection.
this produces a genome that is devoid of the base pair level artefacts that can be observed when molecular genetic tools are used to edit and splice a genome. molecular editing produces sequence artefacts its like leaving a bit of your scissors behind when you cut a string. this is easy to spot; a smoking gun.
artifically directed selection is not easy to spot but would be evident in the case that frequencies of characters or traits are not distributed according to the laws of transmission genetics
Is making biological weapons of mass destruction crazy?
Fauci does not think so.
https://www.washingtonpost.com/opinions/a-flu-virus-risk-wor...
Dangerous things need to be contained really well, regardless of whether this virus leaked or not.
Natural dangerous respiratory virus outbreaks do occur from time to time so it's better to be ready against them which also steels us against lab leaks.
With this GoF research, the potential downside is extremely large. COVID was really bad. As it is, it's responsible for 3.5 million confirmed deaths so far. This is several orders of magnitude worse than Chernobyl.
This isn't even the worst case scenario though. GoF work has also been done with enhanced flu viruses that could have IFRs above 10%. With something like that you could be looking at upwards of 100 million deaths. Those are really extreme consequences, on par with a total nuclear exchange between the US and USSR.
And then, what do we get out of all of this? For all of the Coronavirus GoF research they did, how did any of that help us at all against COVID?
https://en.m.wikipedia.org/wiki/Dual-use_technology#Biologic...
Here's a quote from one of the referenced NIH studies in the editorial which makes it plain:
>"laboratory experiments that resulted in viruses with enhanced transmissibility in mammals"
Gain of function enhanced viruses are inherently dual use, so calling them biological weapons of mass destruction is not hyperbole.