Can you say more about why rDNA is excluded? Does this stand for ribosomal DNA? Like the DNA that codes for rRNAs? Why is that difficult to sequence?
Edit: 200 (http://book.bionumbers.org/how-many-ribosomal-rna-gene-copie...) and its why nucleoli are a thing. This answers so many of my questions about the nucleoli and why so much RNA modification machinery is always found there...