You need to establish channels of enjoyment for your life. Sports, meditation, religion, intimate relationships, vacations, hobbies, etc. Startup life is hard and sucks most of the time for a long time. It gets easier with good people around you and money in the bank, but it's never a walk in the park.

Become resilient by building layers of enjoyment. When problems come, use these layers to dissipate pain. Hope this helps.