Same. I have to work with large separated value files and it can get Emacs chugging on my Mac Book. Also any file large file that has any sort of highlighting (I.E a large xml file) can be difficult to work with.

I'm hoping that GCC emacs will resolve some of these issues. A better Elisp backend will do so much for Emacs and all of it's modes. I think one of Guilemacs goals was to have a better elisp interpreter but I'm not sure they will ever be able to keep up with all the development that has been happening on Emacs