While I'm sure shoplifting is a concern, where I lived (around Market/Van Ness) there were 4 or 5 Walgreens stores within a 3 block radius. And several CVS, Safeway, Whole Foods and many other smaller independent ones on top of that. And I (and everyone I know) still ordered everything on Amazon. A couple of them have since closed, and it was long overdue IMO. Shoplifting or not there was no way they were all profitable.