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Comment by graeme | Hacker News Reader

SARS-COV-1 attacked systems in a similar way. MERS is a multi system virus as well. They are similar to SARS-Cov-2

https://en.m.wikipedia.org/wiki/Middle_East_respiratory_synd...

The big difference here is that now we have the added problem of dealing with ACE2 bindings which affect human lungs/liver/heart/pancreas/etc.

This is a dangerous difference.

> SARS-CoV recognizes angiotensin-converting enzyme 2 (ACE2) as its receptor, whereas MERS-CoV recognizes dipeptidyl peptidase 4 (DPP4) as its receptor.

https://www.nature.com/articles/s41423-020-0400-4

SARS-COV-1 also used ACE2 receptors. In fact your article specifically discusses that, and suggests there was potential to use SARS-COV-1 vaccine development to create SARS-COV-2 vaccines.

The ACE2 receptor affinity is not novel.

Sort of. Very different without getting into the weeds.

https://www.nature.com/articles/s41392-020-0184-0

The common point of origin for all of these is bats, right?

That's what was being researched in Wuhan from what I've read in the media.

You are right to question all of this. The science thus far backs up what you are claiming and the public narrative is shifting.

Thanks. I've learned that a group of lawyers from Germany are filing a massive lawsuit. one of the lawyers took on VW a few years back for the whole Dieselgate thing and won.

> The common point of origin for all of these is bats, right?

The 2004 SARS was suspected to be lab leak. (I'm not sure if this conclusion has been revised since.)

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC416634/

Mers mortality was really scary, 30-40% I read earlier today. Just imagine what would have happened if that spread

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