I can't imagine applying to that many jobs as an experienced dev. My last job transition I narrowed down my search to 3 companies that I was interested in enough to apply & interview, based on combination of compensation, culture, and product. Got an excellent offer from one of them, and still happy 2+ years later.

I know that's a fortunate position to be in, but it's been a job-seeker's market for years. I feel like if you know your skills and value you can afford to be selective and focus your efforts on quality vs quantity. It obviously takes the stress off to already be employed and looking to move/upgrade. You can interview the companies as much as they are interviewing you.