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You know that you've done a good job of optimizing your stack when parsing JS is a bottleneck. Kudos on getting to this point and pushing past it.

Parsing JS becomes a bottleneck when the web page throws a ton of scripts at you.

Last I profiled, something like 30% of the pageload time for gmail in Firefox was parsing the JS.

In the article he says you will see about a tenth of a second improvement on a 1 MB codebase. That's fantastic, but I wouldn't call it a bottleneck.

If each page you load takes 0.3 seconds and your workload involves loading a hundred pages, that's a tangible improvement.