First AstraZeneca dose can safely be followed by Pfizer for second shot

1. Safety in the short term has been confirmed. Not a surprise, but nice to have evidence that nobody insta-died or insta-$bad-thinged

2. « More neutralizing antibodies are produced in this study with Pfizer «. That’s great, but let’s see how well they do when following them around.

I was hoping for a comparison with AZ+AZ, but it looks like they only compared AZ+Pfizer against AZ+placebo.

They say « In the equivalent trials with a second dose of AstraZeneca, this response was multiplied by three«, but you must be very careful when comparing results from other studies with other participants/methods/inclusions, etc.

But what really matters isn’t antibody levels, but how well these groups fare in real life against circulating COVID and its known and unknown, current and future variants.

Not anti-vax, just despise drawing conclusions from small limited studies against big phase 3 trials.