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Being able to discern a difference in a side-by-side test doesn't really mean much.

You can tell which of 2 similar shades of blue is lighter next to each other, but if you were to look at one and then another a day apart you probably couldn't say which was lighter

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It's a good point about optimization of certain things in general. Like, yeah, someone might post a study that in an anechoic chamber you can tell the difference between compressed and uncompressed audio, but how much of a difference is that making for people in the real world? Often when I listen to music, I'm at the gym, or the office, surrounded by all sorts of background noise that is going to impact my experience way more than compression.

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