Anal oxygen administration may save lives
economist.com
economist.com
Reminded me of the scene from an old underwater sci-fi flic (? was it 'The Abyss' https://m.imdb.com/title/tt0096754/), where the deep-divers had to learn how to 'breathe' the oxygenated liquid instead of air.
Speaking of liquid, there was also an example of 'fluid animation' (is it the term?), later also seen in Terminator 2 (the unkillable and self-reassembling T-1000) and other movies.
From https://en.wikipedia.org/wiki/The_Abyss "The breathing fluid used in the film actually exists but has only been thoroughly investigated in animals.[5] Over the previous 20 years it had been tested on several animals, who survived. The rat shown in the film was actually breathing fluid and survived unharmed"
The human body can take vacuum fine if supported. The lung pressure lower limit is the required oxygen pressure plus the vapor pressure of water at body temperature plus the pressure of the carbon dioxide being expelled. Putting your oxygen in a liquid isn't going to change this minimum.
Liquid breathing is being looked into for high pressure environments, not low pressure environments. The human body has no problem with any high pressure it's ever been exposed to, the depth limit for diving is because the dose makes the poison--you eventually hit the point where anything you could put in your tanks is dangerous.
You are referring to oxygen toxicity. There is far more to it than that. At great enough pressure, your body cannot expel CO2.
Why do you need to be so hostile?
In theory it all works and has great benefits for breathing in high pressure environments. In reality I believe the issues encountered were: getting past the feeling of drowning at the beginning, needing very strong lungs for even normal breathing rates, and then transitioning back to air being problematic.
Yeah, this seems to be quite an obstacle, giving the fact how long it may take for lungs to fully expectorate the mucus after a bout of pneumonia.
full disclosure: I've not tried that!
[Annual mean sea surface salinity for the World Ocean] https://en.wikipedia.org/wiki/Salinity#/media/File:WOA09_sea...
The limit for safe drinking water is 1000 ppm.
The salinity of blood is about 9000 ppm.
Drinking it from either end isn't advisable because the osmotic gradient wouldn't transport water it in very fast. It would be safe-ish but not hydrating.
Not sure if this is accurate, it's a show after all, but it doesn't seem too crazy.
https://www.theguardian.com/lifeandstyle/2009/aug/22/shipwre...
Unbelievable!
Tangent time: Florence Nightingale was an early pioneer (maybe the first?) of data-driven medical policies.
She grew up in a time when women hit a ceiling pretty quickly, despite being extremely competent and in her case mathematically gifted.
isn't that slang for anal sex
> The insertion or other voluntary introduction of foreign matter into the anus or vaginal cavity for the sole purpose of recreational misuse (or use) of said item/substance. Similar to butt chugging, with the exception of using non-liquidous matter instead of alcoholic beverages.
Alcohol is one example, where you can die of intoxication, while if you have taken it the more traditional way your body would have reacted earlier to get it out.
The only thing that was debunked was Brett Kavanaugh's lie under oath to congress that boofing is farting.
https://www.urbandictionary.com/define.php?term=Boofing
>Boofing: The act of smirkingly perjuring oneself before the United States Senate Judiciary Committee.
>Boofing: The act of inserting drugs into your anus for a much stronger trip, even though it's named like a synonym for farting. Brett, we googled what boofing means, the definition conflicts with your testimony.
>Boofing: Common slang term used for anal sex in the 1980's. More recently used to describe the act of inserting drugs ( most often tab form or powdered ecstasy) through the anus to more quickly enter the blood stream, also referred to as "thumbing" or "booty popping" Sexual : Last night, my friends and I were boofing Molly!
>Boofing: the act of consuming alcohol via the anus, for rapid buzz e.g. Lance boofed a bottle of Old Thompson
https://www.healthline.com/health/substance-use/booty-bump#:....
>What’s the Deal with Booty Bumping (aka Boofing)?
>Booty bumping, sometimes called boofing, is a way to consume drugs — usually methamphetamine, heroin, or cocaine — by way of your butt.
https://discoveryplace.info/effects-of-boofing/
>Understanding the Dangerous Trend of Boofing
>What is Boofing? Boofing is slang for inserting drugs or alcohol into the anus. People boof to get a faster and more intense high. Because there are a high number of blood vessels located near a thinner surface layer of mucosal tissue in the anus, drug and alcohol absorption happens at a faster rate than ingesting something orally. Just about anything can be boofed: alcohol, MDMA, cocaine, heroin, crushed up pills, you name it.
https://www.forbes.com/sites/brucelee/2018/09/29/what-exactl...
>What Exactly Is 'Boofing' And When You Should Never Do It
>When someone asks you a question, it helps to know specifically what is being asked. For example, if someone asks you, "have you boofed yet," don't answer unless you know exactly what that person means by boofing.
>Apparently Supreme Court-nominee Brett Kavanaugh asked that exact question in his high school yearbook page. During the confirmation hearings this week when Senator Sheldon Whitehouse (D-Rhode Island) asked Kavanaugh to clarify what "boofing" means, Kavanaugh responded that he used the term to refer to flatulence as shown in this PBS NewsHour broadcast:
https://www.youtube.com/watch?v=4ccXpDhMmBY&t=1s&ab_channel=...
>However, the word "boof" does not appear in the lists of synonyms for fart provided by Thesaurus.com or by Ben Applebaum and Dan DiSorbo in a HuffPost article entitled "150 Different Words For Fart."
https://www.huffpost.com/entry/different-words-for-fart_b_34...
Brett Kavanaugh implausibly claimed under oath that "boofing" was a reference to farting, but he perjured himself and lied to Congress on live television. So now we have a Supreme Court justice who ingested drugs through his butt hole, and lied about it by falsely claiming under oath that he was only farting.
Brett Kavanaugh’s yearbook: the “boof” joke, explained
https://www.vox.com/culture/2018/9/27/17905818/brett-kavanau...
Brett Kavanaugh’s questionable definitions of “boof” and “Devil’s Triangle,” explained
https://www.vox.com/2018/9/27/17911728/brett-kavanaugh-boof-...
https://www.youtube.com/watch?v=VRJecfRxbr8&ab_channel=Satur...
>The boofing exchange between Kavanaugh and Judge, along with other terms like “Devil’s Triangle” in Kavanaugh’s yearbook entry, bears significance because it presents a specific picture of the men as having spent a lot of their time drinking, partying, and pursuing sexual exploits in high school — a reputation that followed Kavanaugh to Yale.
>This is the reputation that comes into play in the account of Christine Blasey Ford, who also testified before the Senate Judiciary Committee on Thursday about her allegations that Kavanaugh pinned her to a bed, groped her, rubbed his genitals against her, tried to remove her clothes, and covered her mouth while she tried to scream for help during the summer of 1982. Ford also alleges that Judge witnessed the incident.
https://twitter.com/davidenrich/status/1045416955522535425
>David Enrich @davidenrich Sep 27, 2018
>Based on extensive interviews by me and @katekelly with Kavanaugh's former Georgetown Prep classmates, what he just said about the meanings of "boofed" and "Devil's Triangle" is not true.
Interpreting "boof" as fart in that context makes absolutely no sense. But interpreting "boof" as ingesting drugs or alcohol though the anus is perfectly consistent with his well documented behavior.
Are you also willing to perform the same outlandish logical gymnastics to argue against the widely known definition of "Devil’s Triangle", too?
https://www.urbandictionary.com/define.php?term=Devils%20Tri...
>A threesome with 1 woman and 2 men. It is important to remember that straight men do not make eye contact while in the act. Doing so will question their sexuality. Larry: Did you hear that Eric and Brian were in a Devils Triangle with Sarah last night? Brad: Yeah man, I did, what homo's. Larry: No man, its cool, they didn't make eye contact.
And to argue just as vigorously and confidently that the women who went public to accused him of sexual assault, and subjected themselves to vicious attack and ridicule and death threats, were all lying?
And do you firmly believe it was right for Republicans to refuse to let the FBI investigate the stories and interview witnesses, or to call his friend Mark Judge as a witness to testify under oath, who was present when Kavanaugh sexually assaulted Kirsten Gillibrand, and who could have also addressed who "Bart O'Kavanaugh" he wrote about in his book "Wasted: Tales of a GenX Drunk" was based on?
https://www.newsweek.com/brett-kavanaugh-refuses-bart-okavan...
>During questioning by the Senate Judiciary Committee Thursday, Kavanaugh did not deny that he was the drunken "Bart O'Kavanaugh" who was said to have vomited and passed out in a car in Judge's book. A heated exchange between Kavanaugh and Democratic Senator Patrick Leahy of Vermont left the question unanswered, but suggested Kavanaugh believed Judge was referring to him.
https://web.archive.org/web/20180928120612/https://www.gazet...
>Democratic Sen. Kirsten Gillibrand is blasting Republicans on the Senate Judiciary Committee for failing to call additional witnesses to testify about allegations by Christine Blasey Ford that Supreme Court nominee Brett Kavanaugh sexually assaulted her when they were in high school. The New York senator said Thursday that it is “an outrage” that Republicans did not force Kavanaugh’s friend Mark Judge to testify under oath. Ford says Judge was present when Kavanaugh attacked her.
So is it your opinion that "boys will be boys", and "(shrug) who hasn't been accused of rape at that age (chuckle)?"
Maybe you're only defending him because you acted the same way at that age, but you weren't nominated for the Supreme Court, and you didn't lie about it under oath in front of Congress.
https://en.wikipedia.org/wiki/Tobacco_smoke_enema
>A tobacco smoke enema, an insufflation of tobacco smoke into the rectum, i.e. as an enema, was employed by the indigenous peoples of North America to stimulate respiration, injecting the smoke with a rectal tube.[1][2]
>Later, Europeans emulated the Americans.[3] Tobacco resuscitation kits consisting of a pair of bellows and a tube were provided by the Royal Humane Society of London and placed at various points along the Thames.[4] European physicians furthermore employed these enemas for a range of ailments.[3
And this isn't a joke..... for example, cyclopropane is an excellent anaesthetic gas but no longer used due to the explosion risk. I believe (?) there was a case of a patients throat catching fire on the operating table.
Methane in surgery can lead to flames when surgeons use electrocautery.
Welp.
But to be serious it's risk management and if the patient is definitely going to die of low oxygen then the patient having a risk of dying another way is still a lower risk.
And you thought Master Yoda had grammatical issues.
I'm getting Requiem for a Dream vibes from this.
[0] https://www.webmd.com/lung/news/20210128/china-using-anal-sw...
And here I was, fearing pizza trays and non-stick pans.
[0]: https://en.wikipedia.org/wiki/Per-_and_polyfluoroalkyl_subst...
In the future spaceship air locks will include a box of emergency oxygen suppositories.
https://www.theguardian.com/us-news/2014/dec/09/cia-report-r...
[1] https://youtu.be/Ug5jVUv5V_A
[2] actually a South Park episode. NSFW
ECMO – for patients with too destroyed lungs – is even worse, massive infection risk due to exposing vital arteries and veins, and it destroys your blood cells, requiring constant topping up with fresh blood transfusions.
This has the potential to be less invasive than either measure and could give the patients a chance to let their lungs actually heal from all the damage.
“Laying tubes into the trachea” I presume refers to tracheostomy.
Let’s be realistic here - if you are requiring a tracheostomy and ventilator, or ECMO the you are severely unwell. A blood transfusion, or small risk of infection is the least of your worries at that point.
As with everything in medicine there is a risk:benefit ratio. If you need ECMO you literally cannot oxygenate your own blood even with a ventilator. No ECMO = you die.
Obviously. So why use these invasive procedures if a less invasive one could do the job with less risk?
> A blood transfusion, or small risk of infection is the least of your worries at that point.
Did you come straight from the 19th century or something? Hospital acquired infections kill hundreds of thousands of people every year. That's hardly a small worry.
> As with everything in medicine there is a risk:benefit ratio.
No shit. That's why there's interest in alternative procedures with less risk for the same benefit.
> If you need ECMO you literally cannot oxygenate your own blood even with a ventilator.
Unless… there's a new method that bypasses the lungs. Did you read the linked article?
Clearly if anal oxygen proves to be safer and as effective then it will be adopted. No one is disputing that.
My comment was regarding your expletive laden derision of devices which save hundreds of thousands of lives.
And you seem to have missed the point. I did. It say hospital acquired infections are not prevalent or problematic. My point was that every decision in medicine s based on risk and benefit. If you need ECMO you will almost certainly die without it. If you have ECMO there is a compratively small risk of infection that may kill you.
And yes thanks, I did read the article. I’m also a doctor and have spent many months working in ITU, anaesthesia, and operating theatres, and managing acutely unwell COVID-19 patients.
Let us all be glad you’re not making any treatment decisions.
Could've fooled me with how dismissive you were.
> My point was that every decision in medicine s based on risk and benefit.
Then there should be no problem with highlighting the risks so people realise that alternatives are worth it not just as somehow inferior "second standard" as implied by the person I was replying to, but as equal or better solution.
I don't think _"F### ventilators. They damage the patient's lungs, and laying tubes into the trachea requires traumatic surgery and carries significant secondary infection risk"_ is really offering an informed or balanced discussion of the risks and benefits of intubation and ventilation hence my initial reply.
On the contrary, this offers an emotive, highly negative, and uninformed opinion with no balance. We are in a time of a global pandemic with the general public now aware of intubation, ventilation, ECMO, CPAP, BiPAP, and other respiratory interventions. Many people and/or their families are having to face or consider these interventions. Your comment is potentially harmful.
Against to be clear, the medical profession is (spoiler alert) acutely aware of the risks and negatives of ventilation, including extended ventilation, ECMO, surgical and percutaneous traches, and every other intervention that is offered. These risks are discussed with patients and families who often lack the domain expertise, it therefore being part of the role of the doctor to explain to the best of their knowledge what options the patient has before them and likely outcomes of the different options. Ultimately (ideally) the patient makes a decision for themselves based on this information.
You can be sure that the nuanced and balanced discussion is a little more informative than "F### ventilators".
Yes, they're the least bad treatment options we have right now, I can still be hyped about potential improvements.
> You can be sure that the nuanced and balanced discussion is a little more informative than "F### ventilators".
I'd rather hope so. I've had to ask "so what health risks were you supposed to inform me about according to the form you want me to sign?" way too many times.
If squirting oxygenated perfluorodecane up your ass for two weeks can keep you alive more often than proning or intubation, that'd be a great improvement. Could save a lot of lives. Buy Dow Chemical stonks.
I think it's important to contextualise the risk. The risk of dying from an anaesthetic is about 1 in 100,000. Compare with risk of dying in a car accident in a given year for example.
And again, it comes down to risk:benefit. Anaesthetics are not given out willy-nilly. The reason for the anaesthetic is considered along with the patient's co-morbidities and personal physiological parameter where relevant. Based on this a reasonable estimate of the personalised risks for that patient for that operation can be given for the patient to choose if they wish to proceed or not.
The idea is that this will enable a less invasive way of ventilation for oxygen-deprived patients (i.e., covid-19) than tracheal intubation. It's even possible a patient could be ventilated from (pardon) both ends simultaneously.
https://web.archive.org/web/20210514233706/https://www.econo...
This article reminded me of the bizarre source of the expression to "Blow smoke up your arse":
http://www.todayifoundout.com/index.php/2014/05/origin-expre...
Click reader mode and if the article is truncated there, press reload/F5 to reload while being in reader mode.
If Firefox does not offer the reader mode symbol for a website, you can force loading the website in reader mode by prepending about:reader?url= to the URL.
https://www.snopes.com/fact-check/thai-die/
So, some type of ultra cheap method to get high (but quite dangerous) is to get pump air with bicycle pump into the bottom. Article above.
"The death was not part of a "fad" for getting high"
https://www.youtube.com/watch?v=bznDjbQLzMo&ab_channel=TLC
At least you don't need to use those expensive tasty gourmet beans.
The privilege here is real.