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Well, 0.4% of trial participants actually did have life-threatening reactions, so there's that. The risk is small, but not zero.

As far as mild side-effects go, another way of putting it is that at least as many kids will experience side effects from the vaccine as from Covid itself.

...and millions of kids are going to get this vaccine in the coming months.

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A serious adverse event doesn't have to be life threatening.[1] The difference between groups wasn't statistically significant. And there was no pattern either.

[1] https://news.ycombinator.com/item?id=27114261

My understanding is that Serious Adverse Events are not necessarily reactions that can easily be attributed to the vaccine (unlike a headache occurring soon after the vaccination), so we have to check whether these results are statistically significant and/or whether any patterns can be found in terms of what these events actually are.

I don't think 0.4% vs. 0.1% with n=1127 is significant, and the study mentions no patterns were observed.

We still have systems like VAERS to ensure side-effects that are too rare to be caught by a study of this size still get caught.

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