How on earth do you manage 1000+ tabs? With some kind of add-on software, no doubt, but I would like to know your workflow.
After that I usually bookmark them all and nuke them.
Realistically, part of the idea is that if there's something of vague interest, I middle-click figuring I might revisit it at some point in the future. Usually this isn't the case, but as I know it'll wind up in my bookmarks at some point, there's still that possibility. Sometimes it even happens!
I do something similar to one of the siblings' replies with work though. One window per project/task with all associated tabs (e.g. documentation). Usually these don't get abused as much.