High volume and high gain are two different things, often found working together.
Under extreme conditions the little steel adjusting springs are free to rattle at all frequencies and resonate at some. They are so close to the permanent magnets of these high-impedance pickups that you can really hear it sometimes.
Once you know your desired pickup heights, some players have these springs replaced with precision-matched lengths of flexible plastic tubing instead. Gives a much more limited range of height adjustment though.
Somewhat like the whammy-bar springs in a Stratocaster, if you really crank it with their cover off you can hear it if you "strum" the springs. They can also be dampened.
Bad news is that the most important connections to be well-soldered are in the guitar where everything should be solid as can be, with all dissimilar metals encased by the molten lead alloy.
Changing pickups and changing speakers will still have the biggest effect compared to the slight nuances.