The S54 engine which came before the S65/85, was also high revving, had 11.5:1 compression ratio and didn't have any of the rod bearing issues. The 20v Toyota 4AGE also had them too with a high compression ratio.
The S54 is also notorious for VANOS issues and cam drive failures. I had to replace the solenoid pack on mine but elected to not upgrade the drive while I was in there.
4AGE is 4cyl 11:1 compression producing 155hp with 7200rpm redline.
S85 is 10cyl 12:1 compression producing 500hp with 8250rpm redline.