Surprisingly little alcohol can affect heart rate variability
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span.health
However, a more critical review[0] of the epidemiological data that took into account genetic variants which impact the effect of alcohol intake on longevity shows that the described J-shaped relationship is not as robust as once thought. In conclusion the review simply states:
The optimal level of alcohol intake for health and longevity is zero
[0] https://academic.oup.com/ageing/article/49/3/332/5799035
What I find crazy is that nations around the world collaborate and spend billions of dollars building a particle accelerator and yet we can't seem to find money to research something that affects every human every day of their lives.
Most human nutrition studies are only observational and barely a step above junk science. Don't take them too seriously.
Humans are incredible explorers, self-sacrificing for the greater (perceived) good. We should consider continuing our legacy by understanding ourselves better through rigorous science. (And hopefully end the historical legacy of making thousands of other species extinct via our exploration.)
I believe the Journal of Controversial Idea (https://journalofcontroversialideas.org/) will explore some of these topics, shortly.
So as a practical matter most studies tend to rely on subject reported data, which is notoriously inaccurate. People forget to record little snacks, or don't weigh their portions, or lie about their behavior because they're ashamed.
Yes of course it's expensive which is why I said we should have larger scale studies with more test subjects funded by the government.
Also, what does subject reported data have to do with RTCs? What are you even arguing about?
If you have a better approach for study design then I'm sure nutrition researchers would love to hear it.
Yes, to do a proper RCT you need to confine and monitor subjects in a controlled environment. YOU used the word "years" and nobody ever suggested a study that long. If you're implying that you need a study that long to gather meaningful results then that's just simply not true.
Let me put this plainly, you can design RCTs that are:
A) Safe for participants.
B) Aren't too long.
C) Don't rely on subject reported data.
D) Still give meaningful results.
These are not mutually exclusive and they are done all the time. These are gold-standard experiments in the nutrition field.
Like you said, they are expensive to do and usually only have a small number of subjects. That's why I'm suggesting that wealthy governments should collaborate to fund massive-scale trials at maximum quality.
Best of luck to you. I'm out.
Yes, it is relatively expensive, but not prohibitively so.
Also, as the paper itself admits, drinking small amounts of alcohol has low risks, and while it argues against causation, it doesn't even discuss possible causational factors. E.g., consider the fact that alcohol can reduce stress, which we know has detrimental effects on health. Couldn't small amounts of alcohol be causally responsible then in improving longevity?
Not to be cynical, but I feel the medical community finds this positive low-alcohol/longevity J association rather inconvenient and take every opportunity to debunk it. May be they're right, but if we're to discredit the massive epidemiological evidence, we need more direct evidence and be objective about it.
Here's a quote: "Long-term, heavy drinking can actually alter the brain’s chemistry, re-setting what is “normal.” It causes the release of higher amounts of cortisol and adrenocorticotropic hormone. When this hormonal balance is shifted, it impacts the way the body perceives stress and how it responds to it.21,22 For example, a long-term heavy drinker may experience higher levels of anxiety when faced with a stressful situation than someone who never drank or who drank only moderately" from https://pubs.niaaa.nih.gov/publications/AA85/AA85.htm
You can search for alcohol's impact on GABA, cortisol, or just stress in general and find plenty of science showing that there are significant negative impacts to how the body responds to stress or various key hormones due to damage from alcohol.
https://www.mayoclinic.org/diseases-conditions/allergies/exp...
Here's a summary for the lay reader [0]:
> One way to get around these limitations is through genetic studies. Some people carry a genetic variant that disrupts their ability to metabolize alcohol, causing them to develop skin flushing, irritation and other unpleasant symptoms when they drink alcohol. As a result, they tend to abstain or drink very little. If alcohol was good for heart health, these people should in theory have more heart disease compared to others. Instead, as one large analysis published in BMJ in 2014 found, they have “a more favorable cardiovascular profile and a reduced risk of coronary heart disease than those without the genetic variant.”
> The study concluded: “This suggests that reduction of alcohol consumption, even for light to moderate drinkers, is beneficial for cardiovascular health.”
(One fact not mentioned there is that for this technique to work and identify causality, the distribution of that genetic variant needs to be uncorrelated with all the other relevant variables. To my knowledge, this is true.)
[0] https://www.nytimes.com/2020/07/10/well/eat/should-we-be-dri...
I would argue that, at the public health level, focusing on a naïve "zero level" of alcohol in favour of the "better alternatives" would at best be ineffective, not the least because the better alternatives can be promoted regardless of alcohol consumption. At worst they could even be harmful, if the encouraged abstinence were to discourage the social events associated with non-excessive alcohol consumption.
On an individual level yes indeed, having 0 beers a week may be provably healthier than having 10 beers a week, all else being equal. And that's the crucial point—all else being equal. Those beers are not drunk in isolation or without context. The individual may enjoy trying craft beer with their partner at dinner, or they may meet some friends at the pub and enjoy some slightly disinhibited laughs together. Could this person enjoy trying herbal teas with their partner? Perhaps. Could their friends meet up for a game of volleyball instead? Maybe. Is it realistic to expect similar alternatives to alcohol in the overall population? Very probably not.
Now I can tell you that my social life is exactly the same as before - but I’m drinking water or near-beer or something fizzy instead. I don’t care, my friends don’t care, and if they did, they wouldn’t count as friends anyway.
Now if you’re a frat member, maybe it’s different.
But I will say that being tee total has impacted my experience of social gatherings based around drinking. Sure, with good friends it couldn't matter less. But with work folks, acquaintances etc? Yeah, it matters
For anyone interested, I followed Allen Carr's Easy Way to Control Alcohol. It was a totally painless process for me
I'm not saying alcohol isn't effective, I'm saying that in all cases there are healthier ways (wiser ways) to achieve the positive effects.
I'm not saying alcohol isn't efficient, I'm saying the work required to implement the healthier methods for the same effects is worth the extra effort.
At the public health level, I don't think there's any harm in condemning alcohol. I'm not saying prohibition, and I enjoy a good tequila or whiskey or wine or beer - it's great stuff. But the least of our members of society - those with the worst problems - are often making their lives worse with alcohol not better. I see no issue in messaging that repeatedly. Responsible and irresponsible people will always drink, but messaging the harm it causes more often could not hurt American society. I don't think that's naive at all. You may be confusing messaging "zero level" with a legal prohibition, and I don't think that's a valid equivalency. Exercise is good for you, abstaining from alcohol is good for you too. Just like abstaining from fast food. It doesn't mean everyone will comply, nor should you expect that. But messaging that this stuff is not healthy seems wise to me. Instead you see a steady drip of "a drink a day may be good for your heart" crap, that is assuredly endorsed and promoted by the beverage industry, and not with the health of society in mind.
This is all just an attempt to create moral panic with pretension it is all concern about health. So people are free to point out that.
The whole "little alcohol can actually be healthy" meme is a good example of corporate sponsored research combined with publication bias. https://en.wikipedia.org/wiki/Publication_bias It went on 15-20 years before better and larger studies debunked it.
Alcohol use and burden for 195 countries and territories, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016 https://www.thelancet.com/journals/lancet/article/PIIS0140-6...
>Alcohol use is a leading risk factor for global disease burden and causes substantial health loss. We found that the risk of all-cause mortality, and of cancers specifically, rises with increasing levels of consumption, and the level of consumption that minimises health loss is zero. These results suggest that alcohol control policies might need to be revised worldwide, refocusing on efforts to lower overall population-level consumption.
It ought to astonish me that people unironically think this way, but then I remember one of the most dangerous and life-shortening human tendencies of them all - the desire to control others.
It also is what everyone drinking a few glasses of wine here and there want to hear
I don't think we should rely on any group's anecdotal espousal of the health benefits of their choices.
This is the conclusion of the most recent lancet study on alcohol and health. However, the lancet study comingles societal and personal health affects, which I find annoying (drunk driving, increased violence, etc)
From everything that I've read, alcohol has a j-curve benefit to cardio health, and a j curve detriment to cancer rates. When you look at mortality rates vs alcohol consumption, the J part of the curve doesn't return to 'tee-totaler' non drinker baseline until you're at ~ 4 drinks a day, which is a lot.
"Therefore, although there is a strong body of evidence that shows a J-shaped association between alcohol intake and mortality, it seems likely that the link between low–moderate intake and improved survival is not causal, and there is no ‘safe’ threshold intake below which drinking gives benefit. However, from an individual older person’s perspective, low–moderate alcohol consumption carries only small risks, and these may be counterbalanced by the pleasure obtained from drinking."
Or abstainers lose out on job opportunities/social networking, end up in a lower socioeconomic class and lose lifespan because of the negative effects of that.
Who knows.
This answered a big medical doubt I have had for the past week.
For ages my heart rate has been at a stable 95-105 resting BPM with very little variability, which is quite high and understandable given my low fitness. I've recently radically changed my diet, and in 2 weeks my resting BPM has gone down to around 65 (!), changing rapidly up to 100 BPM if I move unless I'm staying completely still.
I was unsure of what this radical change meant, but apparently whatever I was doing before was very bad for me, and whatever I'm doing now is much better. Given that my diet change has also put my anxiety in remission, it makes sense that there's a strong connection between less overstimulation in the brain and more relaxed circulatory system.
For an example of HRV, let's say you're showing a heart rate of exactly 95 BPM for a one minute period, which means an average of one beat every 0.6316 second. If the actual beats were very close to occurring exactly once every 0.6316 sec like clockwork, then you have a low HRV.
At some later time, you also measure 95 BPM during a one minute period, but this time you find the period between beats is much more variable. Sometimes it is 0.627 seconds, and sometimes it is 0.641 seconds. The beats aren't falling like clockwork, they are all over the place.
The second example is a high HRV, both examples having the same heart rate.
Accurate beat-measuring equipment is required to calculate HRV (e.g. a heart-rate watch and an app).
Oh yeah, and my brain works noticeably better than it has for the past 15 years. It's 100% reproducible for me, but I just need a lapse of judgement, the wrong food, and it's back to the dark pit of doom and extreme tiredness.
Also, ketosis is a superior state of being than the carb/insulin/blood sugar rollercoaster IMO.
My resting heart rate while sleeping is typically 64-68 without alcohol and 65-85 after drinking several glasses of wine. There is such a marked difference in RHR in the two scenarios that you could tell if I drank simply by looking at my heart rate chart during the night.
Interestingly, I attempted to start running for one month about a year ago. My endurance is poor, but I would run/walk for several kilometers. Within the first week and continuing through that month, my RHR while sleeping was 52-62. Not only was it significantly lower, it took a long time after stopping exercise for the rate to return to what it usually is.
I don't know what this all really means, but it is fascinating. Studies or not, I imagine that not drinking + regular cardio exercise is better for long life than the alternative combinations.
That was the biggest effect I saw by far, more than all the sleep apnea variables I was trying to measure!
Granted I don't drink often, and metabolize alcohol poorly, but still that's a huge difference.
FWIW I'm not out of shape; I commuted 1h / day by bike for over a decade, and was a medically normal weight, which is maybe 20-30th percentile in the population.
An RHR that gets into the 85 range could indicate a cardiac problem. Might want to get that checked.
but contrary to the article, an evening whiskey ~3 times a week (in my experience) seems to be optimal for delivering antiseptic benefits with few/no downsides.
When I went back to the article to check this, however, I saw that, while the text says that alchohol has "a negative effect on HRV", and their model explains this, the diagram shows alcohol increasing the HRV. As the text's version of the observed results and its explanation for them are consistent, I assume the diagram is incorrectly labelled.
Update: Thanks to everyone for correcting me on what HRV means here.
It is believed to occur as the parasympathetic and sympathetic nervous system "fight" over raising and lowering the heartrate. The symbiosis between them lands on a steady rate per minute with fluctuations on a per beat basis.
I could try cutting it out, but I've had trouble falling asleep my entire life, and my average annual caffeine intake was very low until my mid-teens. I'm actually much better about sleep now than I used to be, even without meds. Worth a shot, though, I guess. I'd been thinking about dropping my intake to one cup per day, alternating coffee and green tea (which would represent a large increase in my consumption of green tea) anyway. Hell, at lower volume I could justify buying the expensive, low-package-weight, really, really good beans, so the flavor of the coffee I'm drinking would improve, though I might have to group coffee-days rather than alternate them, to avoid issues with beans going stale. Seems like ~halving my caffeine would be an OK start.
Sigh. Guess I'm going to be spending a lot of money on sparkling water, just like when I kicked my soda habit :-)
It surprised me a lot.
However, he theorizes the maximum beneficial dosage is about 2/3 of a single drink.
https://chrismasterjohnphd.com/lite-videos/2018/12/13/is-alc...
https://www.youtube.com/watch?v=lIv96reVlAE
"We were in the background, gently swaying from side to side"
The Apple Watch records this data.
Anecdotally, 1.5 drinks within 5 hours of going to sleep raises resting heart rate by 5%-10%. My friends who have an Apple Watch have similar results.
My personal data on HRV and booze is too erratic to draw conclusions.
We know HRV is "good" as a general matter, as orderliness of heart-rate variation is predictive of mortality post-infarction [sorry no cite; read some papers in the 90's w/ convincing plots of instantaneous heart rate vs ihr 10 beats ago].
The linked research shows an increase in power of the middle part of the spectrum (fft of intrabeat heart rate), which is usually linked to respiratory sinus arrhythmia (RSA, or the change in chest cavity pressure while breathing changes your heart rate).
Anyway, it's interesting, but maybe the value is in the pathway discussion rather than any specific end-effects on health. Would love to hear from people closer to this topic , or OP's specific interest in the matter.
This might be an unpopular opinion: I like the taste of some alcoholic beverages, but the slight impairment from just one and the risk of a hangover is too much. I'd rather drink club soda and lime than imbibe.
Honestly I feel similar. I don’t mind drinking. Taste isn’t an issue and the immediate effects of intoxication are “fun” but I almost always feel like shit during and after the comedown. The after effects of a hangover are in my option worse than most of drugs I’ve tried.
How do you know this?