Like with most simple questions in Ramsay theory no proof or contradiction has been found for the general conjecture, but there has been some progress for some `H`.
The latest paper proves that the conjecture is true if `H` is a cycle of 5 graphs. Since proving this was so hard and provided so much insight, there's hope that the general conjecture can be proved without a lot more work.
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Here's an actual ELI5:
There's a party where some pairs of guests know each other and some don't. A genie told you that there isn't any group of 5 people that only know two people from that group in a way that those relationships form a loop (1 — 2 — 3 — 4 — 5 — 1).
Knowing that, you reason that this cannot be a regular party. Instead, it has to be one of these two:
⒈ A class reunion, where there's a large group of people that all know each other.
⒉ A group blind date, where there's a large group of people where nobody knows anyone.
Being a smart 5-year-old the genie pushes you to publish a 19-page paper proving this, but you find out in Hacker News that some academics beat you and published it this February.