That's just an astounding incidence rate. That kind of selective pressure makes the reason for the sickle cell mutation in hemoglobin more obvious.

https://www.cdc.gov/malaria/about/biology/index.html

> Inheritance of this mutated gene from both parents leads to sickle cell disease and people with this disease have shorter life expectancy. On the contrary, individuals who are carriers for the sickle cell disease (with one sickle gene and one normal hemoglobin gene, also known as sickle cell trait) have some protective advantage against malaria. As a result, the frequencies of sickle cell carriers are high in malaria-endemic areas.

> . . .It was found that that the sickle cell trait provides 60% protection against overall mortality.