I don't think I've ever called out on a library, or not felt truly thankful that it was there to help me. But Sequelize... man...
When I first got into Node, and got Sequelize, after working for years with .NET, Entity Framework, NHibernate and the likes, it just felt like horrible-everything. I've forced myself to use it in some projects, because node is cheap, and I kept thinking that I'm missing something. Some brilliance behind the questionable... everything. No. I can't even bring myself to think about that design mess. Sorry for the rant, Sequelize makes me feel insecure, and little, in the chaos of the Universe.