So many recommendations, but no Trigun yet. Starts off very silly, but goes to some good places over its single season run. At least, I sure felt it did when I was 13.

It's a western/sci-fi set in a vast desert-dwelling society, focusing on the legend of the mysterious criminal Vash, with a 60 billion dollar bounty on his head, usually called by the nickname "Vash The Stampede", who wreaks destruction and mayhem wherever he turns up.

We follow around a goof who looks just like him.