250Hz high pass seems too high for male voices in the baritone or bass range. And depending on whether the female in question is more of an alto vs soprano 250Hz might still be too high.
Using a decent microphone (AKG D5 in my case) and a little bit of tweaking (just a low cut and some compression is a good start) instantly puts your sound quality in voice chats so far above everyone else using cheap headsets or their laptops' built-in mics.
Anecdotally I've found that sounding more authoritative makes people listen a lot more to what you say, instead of zoning out.
Of course if you had it on and were further away from the mic, you'd thin out lower voices. Just goes to show micing people (or instruments) isn't entirely straightforward.
[0]: (Page 4) https://media.sweetwater.com/store/media/u87ai_u87.pdf