I think this would be great if you can bind them to an IDE's Debugger Shortcuts. Step In/Out/Thru.
Some people take this to its extreme conclusion.
It would be so cool to mount a Soviet nuclear control room type panel under my monitor with those keys spelled out. Oh and a mute button.
Sadly it's difficult to see all the mapped keys at once, and the search can't search for the key (only for the action a key might be bound to) so making new maps is a bit tedious. It's possible to do so via making a plugin, but that's probably even more effort.