By enlisting thousands of young women to watch the knobs and dial buttons.
https://outrider.org/nuclear-weapons/articles/women-who-buil...
They didn't even know they were building the bomb. They just had to enter the room, dial knobs back-and-forth for 8-hours/day, and then go home.
Today, that sort of stuff SHOULD be automated. It made sense back then because there weren't computers, but... you really can't just get people to balance knobs 8-hours / day anymore.
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EDIT: https://www.energy.gov/articles/five-fast-facts-about-calutr...
Seems like Department of Energy has some historical articles on them too.