The speed of light ought to remain constant (for inertial observers). So nothing would be different locally as far as I'm aware.
The dipole anisotropy of the Cosmic Microwave Background will continue to be a good tool to see the constancy of the speed of light for all observers into the practically infinite future, assuming the infinite future looks a lot like de Sitter space (which is essentially what the standard cosmology predicts).
http://www.astro.ucla.edu/~wright/CMB-dipole-history.html
The far future of the universe will still have generally covariant physics, as does its far past, sharpening up your second sentence.