I used to, but my requirements evolved out of Qubes and I ended up replicating most of the Qubes environment over KVM.
Are you using alternatives to Qubes tools such as the secure clipboard (qvm-copy-to-vm), or just using a lower security setup?
I have some of my own tooling in place, for example with secure clipboard, I have disabled clipboard sharing between VMs and instead wrote host-level ssh+xclip scripts which I hotkeyed.