Know your product ! Figure out if you want traffic or subscription (are you willing to take a signup loss for long term gain ?) or leads and how qualified.
When you use adwords, they keep offering you to talk to a google representative every couple of month, to review your account and make suggestions. I found those a massive waste of my time when I had a campaign going well, but when I had trouble launching something new they were often a very decent (and free !) help. Make sure to use that and ask any questions you may have then.
Like I said they want to extract as much $ from you as they can, but they clearly know they need you to make money from it too. It's a love / hate relationship, but it works for me.
Best of luck on your venture