This is something I've been musing over recently as well: cars really are responsible for much of what is unpleasant about city life. When people gripe about cities, their complaints are often around:
* Noise. From where I sit, the only noises that filter into my apartment from the city are occasional laughs or shouted conversations from bargoers, loud trucks grinding gears on the avenues, or honking of desperate commuters
* Lack of space. Basically every city block in the USA is surrounded on all sides by areas where, if you walk into them without your wits about you, you could be smashed by a multi ton vehicle. When streets are closed for street fairs or the like, the "lack of space" complaint often drifts away - the whole city is your space again.
* Danger. See above. There is of course also higher crime in cities, which I cannot find a way to pin on cars.
* Grime/poor air quality - pretty self explanatory
I'm hopeful that, with the pandemic increasing interest in the outdoors and making cities have to work harder for their tax base (because WFH means they can no longer rest on the "you have to live here to get a job" that they've been reliant on), city governments and voters will realize how much can be gained by dialing back on car investment.