One specific case that cripples Elixir - is as far as I know Elixir can't handle large multiplications efficiently. Ruby, Python use karatsuba or some derivative - from what I can tell multiplication in Erlang doesn't. Though I haven't actually asked anyone and was just poking around on my own.
example: Multiplying the first 100_000 numbers together I get
ruby multi.rb 3.47s user 1.91s system 99% cpu 5.396 total
elixir multi.exs 14.32s user 0.62s system 103% cpu 14.441 total