I'll wait for more and longer term studies before I try it. Maybe it slowly erodes teeth, or destroys amalgam fillings since it's EDTA.
EDTA is used in food, medicine, and dentistry. It's ingested, inhaled, and injected into people every day.[1]
In the video you linked Adam Savage reads out the safety warnings from the Evapo-Rust bottle ("non-toxic, biodegradable, safe on the skin and eyes") and from the Evapo-Rust SDS[2] it seems like a pretty darn safe product.
[1]https://en.wikipedia.org/wiki/Ethylenediaminetetraacetic_aci...
[2]https://evapo-rust.com/wp-content/uploads/2018/08/Evapo-Rust...