There is however a difference between: earning money as a goal and improving lives as a means (improved quality of life being a byproduct) and wanting to improve lives (and as such quality of life) and earning money only being a requirement to sustain those activities.
But perhaps startups are not way to go for the latter, which is why I am curious if there are any startups taking this route (or perhaps have tried and failed).
This is one of the reasons Twilio excites me so much, incidentally. (Disclaimer: commercial relationship.) Cheap mobile phones have been a huge, huge, huuuuuuuuuuuuuuge win for the global poor. Twilio (and companies like it) upgrade every phone in the world to being a smart phone. I think that's going to create wealth on the scale of the Green Revolution or the Internet eventually.