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Comment by andrewcl | Hacker News Reader

Cool, but it's the lipid delivery system that is the secret sauce. This is equivalent to giving the source code without a compiler to build it.

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Wouldn't the "compiler" be the bioreactor used to mass-produce it and the "installer" be the lipid encapsulation? :)

InstallGene by Flexera

Just waiting for first copy protection mechanism for mRNA. SafeGene and SecuGene here we come :o

Can you imagine, the greedy folk would want some sort of Widevine in humans.

The vaccine will check your implanted payment chip receipt number before activating the payload.

"Drink Brawndo, The Thirst Mutilator." in your DNA too.

Sony is gonna sneak in some DRM and Mark Russinovich is gonna put out a fix.

"The authorization server is down, no longer signing this version of this medication, or this medication has expired. Please contact your supplier for more information."

Shit, I'm going to have to google for a working hex edit or look for a bpatch.

Can't wait for the DNA "chip art" by gene designers. Considering we have so much HERV, they might use that as an equivalence rationalization to do it.

Maybe the booster shot can be done with a simple apt-get update.

a fellow linux user. ubuntu?

Got the “GPG Error: No Public Key” error. Probably for the best!

Fawwwwwk. Gotta edit the /etc/apt/apt.conf.d/covid-19-vaccine.conf

Anyone know if sudo works?

Serious. Unless it requires a separate, native-compiled adaptive immunity package.

In the case the bioreactor “compiler” is actually our own cells which read out the mRNA “source code” and translate it into protein. The lipid encapsulation delivers the mRNA to our cells, so perhaps it’s more analogous to a network protocol that delivers source code intact across firewalls and other defenses.

But wasn't the whole Pfizer/BioNTech "secret sauce" leaked online after the EMA was hacked?

Meh, they probably just used lipofectamine (which has been around since the 90s) or something very similar.

https://en.wikipedia.org/wiki/Lipofectamine

https://www.thermofisher.com/us/en/home/brands/product-brand...

lipofectamine is used for in vitro transfection, not in vivo gene delivery. The vaccines use lipid nanoparticles rather than liposomes

If they didn't use lipofectamine, what did they most likely use?

Derek Lowe discussed it a few months ago:

https://blogs.sciencemag.org/pipeline/archives/2021/01/11/rn...

https://blogs.sciencemag.org/pipeline/archives/2021/02/22/mo...

I absolutely do not have a link, but I remember reading that the lipid nanoparticles are actually created by mechanical action (possibly fluid dynamics/turbulence). I thought that was pretty neat.

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