Broadly speaking, the big regulations tend to create conditions where disruption is harder. Regulatory compliance is often a substantial investment, and a rather big one, thus a barrier to entry; it's a lot easier for big, profitable Google to hire a team of regulatory compliance officers and GDPR architects and the like than it is for a small startup.
However, the reason for those requirements isn't, ostensibly, to make disruption difficult - it's to protect the society from problems that can be caused by companies of all sizes equally easily. For example, safety regulations about medical equipment. Or data protection regulations. To the extent these laws make disruption difficult, it's often unfortunate cost of safety.
(I understand though that the real world isn't perfect and big players tend to influence these laws to their benefit. But perfect being the enemy of good, and all that.)
Perhaps not. But public choice theory is chock full of unintended consequences.