We use it at work, and 95% of users have issues with it.
I have to open, close, then open again the macos client every single day when I start it because my keyboard shortcut doesn't work otherwise.
I don't even mind the horrible UI/UX if it actually worked as expected.
Don't missundertand me, on a technical level Mumble is impressive and can do voice channels with thousands of participants, but on the clientside its just a mess.
But the audio setup and tweaking was a nightmare. It was the biggest problem for every participant to tune and tweak their levels in a way that would work good, it was very, very frustrating.
The chat was also super barebones and of course no way to stream video.
It would be great if someone could make a modern Mumble client.