Hacker News Reader

Encode smaller bits of the same protein? Who cares.

Otherwise, the mRNAs aren’t present in high enough quantities to do significant signaling or silencing things, and it’s going in the deltoid... not really a medically interesting place. You could inject 1mL of dilute HCl there and it wouldn’t be a big problem.

View on HN

I'd rather not be injected with bits of mRNA that encode random bits of proteins, thanks. The deltoid is "medically interesting" enough to produce Covid spike proteins.

Won't non-intact mRNA without a stop codon get degraded by Non-stop decay?

you have the idea right , but it isnt a stop codon its a signal sequence on the mRNA that would give it a hall pass.

no cytoplasmic nucleotide transport signal and it gets degraded quickly.

Don’t get the vaccine then, because you are getting small pieces of mRNA.

Proteopathy is a real thing. Prion dysfunctions can cause self-replication, not that the makeup is necessarily there for that in these vaccines. Interesting starting point for consideration nonetheless.

Reply on news.ycombinator.com