My friend just told me about a potential gene therapy. I'm blanking on the name, but there is a gene which inhibits myelin regeneration, and a gene which inhibits that gene. By using an adeno-associated virus which has an affinity for CNS tissue, you can induce the latter, resulting in an increase in re-myelination.

My friend's partner has suspected MS. They are also experimenting with helminth therapy. They have taken 5 Necator Americanus eggs and anecdotally, their symptoms have not been progressing as fast.

A quick search shows a whole mess of various genes and proteins associated with myelin but I'm not sure what the front runners are.

Edit: it's LINGO1

> Lingo-1 antagonists are able to promote re-myelination in CNS by means of stimulating OPCs differentiation which was before blocked by this protein. This has been seen in several experiments that resulted in significant increases of oligodendrocytes differentiation by targeting Lingo-1 with its antagonists, such as the antibody Anti-LINGO-1 (BIIB033)

https://en.m.wikipedia.org/wiki/LINGO1

I have no background at all in this but the link sent me down a rabbit hole of learning about myelin being comprised of carbohydrates and lipids.

Lipids have their own wikipedia page and apparently one of many ways to get lipids is vitamin D.

And of course carbohydrates seem to refer to sugars because the wikipedia article seems to say that myelin is made up of glucose.

But that only says what components you need, not what makes the body produce myelin.

Psychedelics.