- barefoot is better, especially with a low tech mat to make a soft surface. I never wear shoes while working and I don't regret it.
- the first few days are a bit tough, you may experience some back pain. Nothing too hard, but depending on your body that could last up to one week from what I've heard. After that, I'd never go back to sitting all day. It just doesn't reasonate with me anymore.
- the desk that you intend to use will make a hugr difference. I got mine at Ikea after seeing a recommendation here on hacker news. It's basically a desk with three adjustable panels, put the bigger in the middle http://www.ikea.com/ca/en/catalog/products/60111123
- it's important that you experiment with a few heits if you're unsure. A couple of inches can make a big difference. Make sure that you eyes are watching slightly below to avoid neck pain.
If you work from home, you'll love it. You can literally think while walking around your room, there's no resistance rom a chair. You'll take more breaks and feel better overall. And if that doesn't work for you, you can always go back to a regular chair.