When I started in a project that made use of tailwind, I initially exactly felt the points the author is making here: The HTML is a mess, dev-tools don't play as nice, why would anyone like this?

Unlike the author though, I have grown to love it - not having to look at two files to understand what's going on (html/css) really felt like a big boon, especially for "trivial" UIs that just need a bit of flexbox, css-breakpoints and a margin here and there to get going. For more complex stuff, falling back on custom classes is still perfectly fine.

Also, the "html becomes a mess" argument was only an initial issue. Once you get used to the tailwind-classes, most of it becomes fairly readable - the examples of the author are, in my opinion, just as unreadable in css, especially if you're not a design-oriented css-geek (like myself).