What worked well for me was quiting mixing backpacker circus with less known destination. It was fun to sleep at hostels, party with fellow travelers and have fun, but it gets old after while. I split my trips into 3 to 6 months chunks after which I just come back to one of my bases, recharge for a bit and then went to somewhere else. I usually mix things us so after 6 months in SE Asia, I went to Balkans, then Japan and then somewhere more popular with backpackers like Argentina.
It is great experience to have, but I would not put much hope in being truly transformative. Now, almost, 10 years later it just feel like it never happen, memories are fading fast as I went with settled life.
People are often scared about their career outlook or other long term consequences, but I didn't experience any of those.