As far as I know, whether the difference has biological or cultural reasons is not equally well established. But it seems somewhat stable across cultures, which seems to me to suggest that it’s indeed biological, see e.g. Costa et al (2001), Gender Differences in Personality Traits Across Cultures: Robust and Surprising Findings: https://www.researchgate.net/publication/11825676_Gender_Dif...
“In brief, gender differences are modest in magnitude, consistent with gender stereotypes, and replicable across cultures. Substantively, most of the gender differences we found can be grouped in four categories: Women tend to be higher in negative affect, submissiveness, and nurturance, and more concerned with feelings than with ideas.“