I went for a 500km+ drive on Sunday to visit new supercharger locations (it's been a long pandemic and I'm pretty bored). It was mostly rural highways without lane separation or limited access. These are some of the most dangerous roads to drive on since there is direct oncoming and cross traffic. Speed limits are 80 km/hr, but the prevailing traffic flows at just under 100 km/hr, so closing speeds are around 200 km/hr.
I hardly ever turn on autopilot since it's just bad at driving, but there were long stretches of completely straight roads with multiple minutes passing between oncoming vehicles. Even in that specific circumstances Autopilot made some truly weak decisions about its basic driving style.
It attached to the centreline between lanes which limited the gap with oncoming traffic. When I drive myself in the same circumstances I attach to the outside of the lane to maximize the space I can give oncoming cars. With the amount of room autopilot was giving even a small twitch or moment of distraction would be enough for disaster. If the event was timed poorly enough even a computer system would have no chance to react in time to physically manoeuvre the car out of the way.
Autopilot makes no accommodation for blind spots. When traffic is flowing at full speed on limited access or other multiple lane highways I adjust my relative position with other vehicles to ensure I'm never spending long periods of time in another driver's blind spot. If we're travelling the same speed I create a gap to ensure a quick lane change won't result in contact. Autopilot will continue along completely oblivious and no taking good defensive driving precautions.
There is a youtube channel featuring collision footage from Tesla onboard cameras. Nearly every collision when autopilot is engaged is a situation that never would have occurred in the hands of a skilled driver who anticipates issues and prevents dangerous situations from every occurring. Without knowing the specific collision that's about to happen in the video in most cases I can see a dangerous situation starting to develop I would have reacted to seconds before the collision actually occurs.