I've watched my girlfriend use her computer, and this is essentially how she works. She just leaves everything open, never saving anything. She's comfortable using Expose to manage the million windows she ends up having open, but doesn't bother exiting apps when she's done with them and then starting them when she needs them again.
If she could do this and have everything always auto-save and be instantly available anywhere she went, she'd be ecstatic. And even though I grew up on the Windows 95 model of apps and documents... I gotta say I kinda see her angle. I hate that our IT policy makes us log out every night so I lose my windows. If I left for the night then came back and the cleaning person had put away all the papers on my physical desk I'd have a fit!