Reminds me of a former colleague of mine who was one of the principal developers behind an Android app, where they could really go to town on making it crash free, since Android offers a phone home function when a crash occurs.

At some point, he made the observation that 1-2% of crashes occur not because of a programmer error or anything, but "chance"; bit flips and the like, in either the app's memory or the phone's services.

So while on an individual basis it's rare, and in practice nobody will really notice an issue, statistically bit flips are significant enough to need attention.