Hi! Michael here - one of the cofounders. That sounds great and would love to chat! What kind of tissues are you looking at and what are you trying to achieve?
As for the size of data - it's definitely a tradeoff here. We're seeing more and more scientists already uploading their data to the cloud however. We even integrate with data stores like S3 already so you can hook into data you've already uploaded.
We're also looking to build out a pipeline builder - where you can process images in real-time, so this would be less painful, as well as a Dropbox-like mini tool so data would be uploaded as you acquire it.