For jnorthrop generally these events are effectively deflected by the Earth's magnetosphere, however we don't know what we don't know. Its hard to estimate whether or not any one of the extinction events this planet has experienced over the past was caused by solar activity.
I would hope it would add impetutus to efforts to surviving large changes in the Earth's envioronment by creating completely controlled environments (ideally across several planetary bodies) but I have low expectations that it will.
One of the science stories I've been following for a while has been the growing body of evidence that a magnetic pole reversal [1] is becoming more likely. (Note there was a hoax around it changing instantly in 2012 which has been pretty thoroughly debunked). One thing that is pretty well understood is that during reversals the magnetosphere is greatly reduced [2] which suggests that the simulataneous occurence of a CME and a reversal of the poles resulting in a reduced magnetosphere would be something to write home about.
[1] http://www.nasa.gov/vision/earth/lookingatearth/29dec_magnet...
[2] http://www.off-ladhyx.polytechnique.fr/people/willis/papers/...