The basic premise of transhumanism rests on the idea that humans should transcend nature and shape the world and all life, including humanity, into a world shaped by humans.
I really despise this idea for so many reasons...
Humans, despite their arrogance are incapable of even basically managing this planet. We know basically nothing about its proper functioning and we arrogantly assume we should take responsibility of it all and shape it and all the life here as we choose.
Humans have barely managed to keep a functioning society together in the brief 10000 years or so we've been trying to have one. 6000 years if we're going back to the beginnings of agriculture and such.
To think we have even the slightest idea as to how to control nature and this world that's existed for billions of years is completely ridiculous.
The fundamentals of transhumanism are no different than the fundamentals that led judeo-christian religions to exploit and destroy the world.
The idea that somehow, either through divine gift or supreme intelligence, this world belongs to us and should be used and shaped how we please.
We presume we should expand beyond life itself, yet all we manage to do on this earth is destroy and conquer.