Multiple boot floppies? Never had to do that. I was very excited by the new version of DR-DOS that let you build a menu system in CONFIG.SYS to load a different set of drivers and memory managmemt at start up.

Also the wierd IRQ issues. Simpler when you had to set them with header pins on the card in question. When early plug and play came in it was awful, automatic IRQ conflicts and sometimes no way to change them. Was a real pain when the knock off sound blaster clone I had would auto assign itself anything other than IRQ 5 and some games would stop making sounds!