SARS-CoV-2 causes brain inflammation and induces Lewy body formation in macaques

biorxiv.org

41 points·DanielleMolloy··5 comments

This is an unreviewed preprint, treat it with considerable skepticism. Very scary if true, "COVID brain" could be Lewy Body Dementia, even in the asymptomatic. I hope not.

Wondering how this compares to other common diseases. Unfortunately some more context would be useful for us laymen to understand the implications.

Indeed, I had posted it here seeking more informed opinions by people who have followed long covid research during the past year.

When it appeared on biorXiv yesterday a couple of researchers picked it up with worried statements. What I could assess myself were the position of the authors, and format details which look as if they expect high impact (I’m in a whole different field, so take that with a grain of salt).

Maybe scientists will have reason to check in humans next after this result..

The last sentence is a decent summary: “More confirmation is required, but the observations in the translational macaque models for COVID-19 (12-14, 38,39) can be regarded as a serious warning as they may be predictive for COVID-19-related dementia cases in humans in the future, even after an asymptomatic infection or mild disease process.”

Will vaccines have a suppressing effect?

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